Martine (Oliva Thirlby), an artist from New York, arrives in Los Angeles to work on her film. She is staying with friends of a friend, Julie (Rosemarie DeWitt), her husband Peter (John Krasinski), Julie's teenage daughter Kolt (India Ennenga), and their young son. From the day that Martine walks into the lives of this open-minded, relaxed California family, everything is subtly set off balance. Peter is helping Martine complete the sound design on her art film and they collaborate closely together, working in the studio off the pool house where Martine is staying. They develop a connection that is rare for Peter and necessary for Martine to finish her movie but, which begins to veer away from professional terrain. An attraction is also brewing between Martine and David's assistant (Rhys Wakefield), who's sixteen-year-old Kolt is crushing on as well. Meanwhile, Julie, a therapist who prides herself on being professional and together, is fending off the projective impulses of one of her patients (Justin Kirk), a screenwriter who can talk his way into anything. Each character in Nobody Walks experiences a surge of desire catalyzed by Martine's arrival, and everyone is forced to confront the new landscape that emerges in her wake.