Tom Cameron, aka The Lone Rider, and his pal "Fuzzy" ride out to Gunsmoke Valley looking to buy a ranch. They thwart a lynch mob attempting to hang ranch owner Jack Stewart for cattle rustling. When another attempt on Stewart's life is successful, Cameron himself is jailed. With Fuzzy's aid, Cameron escapes and seeks refuge at a nearby mission. Disguised as a padre the Lone Rider hunts for clues to disclose the identity of the true killers.

Former opera singer George Houston would play the Lone Rider in eleven Producer Distribution Corporation productions before being replaced by Robert Livingston. It's curious that this series was named The Lone Rider as he always had a constant companion and sidekick in Al "Fuzzy" St. John. Sometimes he even had two pals, such as in this film where "Fuzzy" is joined by Dennis "Smokey" Moore.